https://www.light-leili.com/home daily 1.0 2025-08-12 https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/5c90a818-7a42-42b9-b878-6e8ab9502331/figures.jpg Home - Single-Impulse Panoramic Photoacoustic Computed Tomography (SIP-PACT) Single-impulse panoramic photoacoustic computed tomography (SIP-PACT) is a dream machine that integrates high spatiotemporal resolution, high sensitivity, and deep penetration. It allows longitudinal monitoring for drug delivery and chemotherapy. SIP-PACT also offers a powerful tool for mapping large-scale neural activities and studying the whole brain functions. It has been scaled up for human breast cancer diagnosis and human brain functional imaging. https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/1629527402491-OM7LU2CIF7O1HOX2XYXD/RSPAT.png Home - Super sensitivity and specificity: Integration of multiscale PAT and photoswitchable proteins The integration of the photoswitchable phytochrome probes with PAT achieves ultrahigh detection sensitivity, high contrast, and multiscale imaging for the first time. It monitors tumor growth and metastasis inside the deep body and achieves quantitative multicontrast imaging in deep tissue—a task that previously could not be done reliably. https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/1629526883219-II4FKTU8UF3TEC5XGGJD/microrobots-use-for-tumours.jpg Home - PACT-Guided Microrobots For Targeted Navigation in Intestines In Vivo In science fiction, microrobots enter our bodies and cure diseases in hard-to-reach areas. However, in reality, microrobots easily get lost after entering our bodies. Locating, guiding, and controlling the microrobots inside the body is a challenging issue. Just like the satellites in space guiding our cars to destinations, a photoacoustic imaging system outside the body can serve as a GPS for the microrobots. It can locate them inside the body in real time. https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/1629529692063-KYSASWNI74U22K6TMKJ4/PATER.png Home - Photoacoustic topography through an ergodic relay (PATER) By encoding spatial information with randomized temporal signatures through the ergodic relay, snapshot widefield high-throughput photoacoustic imaging has been realized, capturing widefield images with single laser shots. It significantly reduces the size, complexity, and cost of the photoacoustic imaging system and holds great promise for wearable and portable medical devices. https://www.light-leili.com/highlight daily 0.75 2022-01-01 https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/f190eb2c-d950-47cd-966b-770d0429bb6c/rq2.png Highlights & Updates https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/00acf68e-dbc1-4269-9e00-9e0e508e3a18/rq3.png Highlights & Updates https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/08f64cff-96ec-4020-95f1-d9b300dc7870/rq4.png Highlights & Updates https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/20cf24cc-9d58-4594-a8fd-9b694d7dae39/5.jpeg Highlights & Updates https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/255ce066-43e7-4d1d-8d0c-9d19479768f9/1.jpeg Highlights & Updates https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/63b507b3-6aa9-4dbf-b2af-267b7303c84a/2.jpeg Highlights & Updates https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/5bbdbdae-4cba-4f37-9dc5-8a1b880e0aeb/3.jpeg Highlights & Updates https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/0e1d50dd-37fd-4b3f-8d95-9e717b4c4e92/6.jpeg Highlights & Updates https://www.light-leili.com/publications daily 0.75 2021-12-15 https://www.light-leili.com/pact-microrobots daily 0.75 2021-12-30 https://www.light-leili.com/sip-pact daily 0.75 2021-12-30 https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/5c49c58a-503c-411e-b8e0-752886dc8389/5.jpeg Single-Impulse Panoramic Photoacoustic Computed Tomography (SIP-PACT) https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/0dcc0fc9-dc65-4c9f-9dad-92a10375294d/6.jpeg Single-Impulse Panoramic Photoacoustic Computed Tomography (SIP-PACT) https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/364c1974-4ee1-4ad6-aeb3-f257127aba95/4.jpeg Single-Impulse Panoramic Photoacoustic Computed Tomography (SIP-PACT) https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/7a7d2053-4cdb-44b7-8c49-2deab7e83e2b/3.jpeg Single-Impulse Panoramic Photoacoustic Computed Tomography (SIP-PACT) https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/38f3edec-6a4e-48df-9bb7-5a4ba09f1377/2.jpeg Single-Impulse Panoramic Photoacoustic Computed Tomography (SIP-PACT) https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/b834a2e0-5ef1-48af-8a71-aabc5811abb6/1.jpeg Single-Impulse Panoramic Photoacoustic Computed Tomography (SIP-PACT) https://www.light-leili.com/rspat daily 0.75 2021-12-30 https://www.light-leili.com/pater daily 0.75 2021-12-30 https://www.light-leili.com/overview daily 0.75 2022-01-01 https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/e0ad146b-8015-455f-b80b-a83cce837d03/SIP.png Overview Single-Impulse Panoramic Photoacoustic Computed Tomography (SIP-PACT) https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/0e6eb173-4ea1-4487-8b76-78043421d406/RSPAT+%282%29.jpg Overview Super sensitivity and specificity: Integration of multiscale PAT and photoswitchable proteins https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/216587dc-90e9-4ef5-a6d5-6e11d2eb046a/microrobots-use-for-tumours+%281%29.jpg Overview PACT-guided Microrobots For Targeted Navigation in Intestines In Vivo https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/9e39192b-0c2f-43f3-8f7e-38cac4e2ed9a/PATER+%281%29.jpg Overview Photoacoustic topography through an ergodic relay (PATER) https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/2e695240-506f-4257-acb0-ced3110254e3/PAM.jpg Overview Label-free photoacoustic microscopy: super speed and super contrast https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/ee9aa3bc-c231-40d9-b56c-d5852c882195/why+light.jpg Overview - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/03481031-57f5-44e8-a5b5-2d55ed2db137/TED+Lei+V7_11.jpg Overview - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.light-leili.com/photoacoustic-microscopy daily 0.75 2021-12-30 https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/9a6f2d97-26b2-4993-a4fc-b693bc0b138d/Picture7.png Label-free Photoacoustic Microscopy a,b, ULM-PAM images of lipids (a) and proteins (b). T, tubular structures; N, nucleic region. c, UV-PAM image of nucleic acids. d,e, MIR-PAM images of lipids (d) and proteins (e), imaged at 3,420 nm and 6,050 nm, respectively. f, Comparison of line profiles along the dashed lines in the ULM-PAM lipid (a), ULM-PAM protein (b), MIR-PAM lipid (d) and MIR-PAM protein (e) images. g, Composite image of a cell formed by overlaying the images of lipids (a), proteins (b) and nucleic acids (c) in different colour channels. h,i, Composite images of the cells at neonatal (h) and mature (i) stages. AB, actin bundle. Scale bars, 10 µm https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/4564f491-7cd0-40a9-b512-964c80cecb2c/Picture8.png Label-free Photoacoustic Microscopy a,b, MIR-PAM images of myelin in slices of the cerebrum (a) and cerebellum (b). RC, retrosplenial cortex. c, Close-up image of myelin. d, ULM-PAM image of myelin. e, PA histology image. f, LFB-stained histology image of the same area (I) in (a). g, Close-up MIR-PAM image of myelin. h, ULM-PAM image of myelin. AB, arbor vitae region; G, granular region. i, Photoacoustic histology image. j, LFB-stained histology image of the same area (II) in (b). In the photoacoustic histology images, green represents myelin and violet represents nucleic acids. In the LFB-stained histology images, blue represents myelin and deep blue represents nucleic acids. https://www.light-leili.com/team daily 0.75 2026-02-12 https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/938ce1e0-ee18-4a7f-a7fd-b2daf121ad1e/songzeli.jpg https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/08ca234b-2d6e-43d9-9ad3-dd309bd9b11e/dr-maslov.png https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/5d5d9f69-ae8f-48ab-aa41-c66b9d907d57/1545-RMV-MSCT-Clear.jpeg https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/c9a6143e-c7b5-4f47-b7df-3189cff386cc/unnamed+%2811%29.png https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/afe7af7e-0340-4793-93d7-d5387f1b56b1/shunyao.png https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/7b1e0755-bb53-46c7-83cb-09eb4f71ed3f/jingyi.png https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/4ca79e46-a0c3-412d-98ec-2d2b7782a668/eric.jpg https://images.squarespace-cdn.com/content/v1/611d8e2afc22922ade2df543/4b9539c4-6316-4094-8ee8-1a15328177b1/mingze.png